Optimized Chronic Care for Smokers: Developing and Implementing Integrated Clinical and Systems Intervention in Primary Care – Optimization Core
Funded by: National Cancer Institute
Project dates: September 2014 - April 2025
Principal Investigator: Collins, Linda M.

Tobacco smoking is the leading preventable cause of cancer death. However, healthcare systems have not realized their potential to reduce smoking prevalence; far too few patients who smoke are offered and use smoking treatments and such treatments are insufficiently effective. This Program Project addresses these key obstacles by developing an especially effective comprehensive chronic care smoking treatment to reduce smoking prevalence in healthcare via 4 individual projects and 3 cores. This Program Project balances internal and external validity via powerful, innovative research methods such as the Multiphase Optimization Strategy (MOST) while also using real-world primary care clinics, patients, and staff, and using the RE-AIM framework to enhance its public health impact. We will develop a chronic care smoking treatment for healthcare that includes optimized reach and cessation interventions that can be readily implemented and disseminated and that markedly increase the use and effectiveness of cessation treatment, ultimately reducing smoking prevalence and cancer deaths.

Abstract on NIH RePORTER
Related Publications
Cook JW, Baker TB, Fiore MC, Collins LM, Piper ME, Schlam TR, Bolt DM, Smith SS, Zwaga D, Jorenby DE, Mermelstein R (2021).
Evaluating four motivation-phase intervention components for use with primary care patients unwilling to quit smoking: A randomized factorial experiment
Addiction, 116 (11), 3167-3179. doi: 10.1111/add.15528. PMCID: PMC8492501.