ResearchProjects

Metropolitan Trajectories of HIV Epidemics, Drug Use, and Responses in US Key Populations
Funded by: National Institute on Drug Abuse
Project dates: June 2014 - March 2020
Principal Investigator: Friedman, Samuel
Principal Investigator: Cooper H (Contact PI)
Principal Investigator: Hatzenbuehler ML
PROJECT DESCRIPTION

For over 30 years, almost all studies of HIV/AIDS epidemics and programs have focused on one key population (e.g., injectors, men who have sex with men, or heterosexuals) in isolation from other key populations. This approach has significantly limited scientific understanding of the fundamental dynamics of HIV/AIDS epidemics. Research analyses have suggested that HIV/AIDS epidemics and programs in one key population may affect epidemics and programs in other key populations. Likewise, programs targeting one key population may affect epidemics in other key populations. This study pioneered a novel line of high-impact epidemiologic, programmatic, and policy research on whether and how HIV/AIDS epidemics and programs affect one another across three key populations (i.e., men who have sex with men (MSM), people who inject drugs (PWID), and heterosexuals) in the US. Findings will open up new arenas for intervention, including interventions that seek to prevent epidemics in one key population from affecting epidemics in other key populations, and that maximize positive effects of interventions across key populations.

Abstract on NIH RePORTER
Related Publications
Williams LD, McKetta SC, Stall R, Beane S, Ibragimov U, Tempalski B, Hall HI, Johnson AS, Wang G, Friedman SR (2024).
Structural discrimination against and structural support for lesbian, gay, and bisexual people as a predictor of late HIV diagnoses among Black men who have sex with men
Journal of Urban Health, 101 (2), 426-438. doi: 10.1007/s11524-023-00818-8. PMCID: PMC11052741.

Williams LD, Tempalski B, Hall HI, Johnson AS, Wang G, Friedman SR (2021).
Trajectories of and disparities in HIV prevalence among Black, White, and Hispanic/Latino high risk heterosexuals in 89 U.S. metropolitan statistical areas, 1992-2013
Annals of Epidemiology, 64, 140-148. doi: 10.1016/j.annepidem.2021.08.015. PMCID: PMC8747890.

Wise A, Kianian B, Chang H, Linton S, Wolfe ME, Smith J, Tempalski B, Des Jarlais D, Ross Z, Semaan S, Wejnert C, Broz D, Cooper H (2021).
Place-based correlates of exchange sex among people who inject drugs in 19 U.S. metropolitan areas, 2012
Archives of Sexual Behavior, 50 (7), 2897-2909. doi: 10.1007/s10508-020-01883-9.

Williams LD, Stall R, Tempalski B, Jefferson K, Smith J, Ibragimov U, Hall HI, Satcher Johnson A, Wang G, Purcell DW, Cooper HLF, Friedman SR (2021).
Trajectories of and disparities in HIV prevalence among Black, white, and Hispanic/Latino men who have sex with men in 86 large U.S. metropolitan statistical areas, 1992-2013
Annals of Epidemiology, 54, 52-63. doi: 10.1016/j.annepidem.2020.09.004. PMCID: PMC7932556.

Ibragimov U, Beane S, Friedman SR, Tempalski B, Williams LD, McKetta S, Adimora AA, Wingood GM, Stall RD, Hall HI, Johnson AS, Cooper HLF (2021).
Evidence for HIV transmission across key populations: A longitudinal analysis of HIV and AIDS rates among Black people who inject drugs and Black heterosexuals in 84 large US metropolitan areas, 2008-2016
Annals of Epidemiology, 55, 69-77. doi: 10.1016/j.annepidem.2020.10.003. PMCID: PMC7923960.

Hatzenbuehler ML, McKetta S, Goldberg N, Sheldon A, Friedman SR, Cooper HL, Beane S, Williams LD, Tempalski B, Smith JC, Ibragimov U, Mermin J, Stall R (2020).
Trends in state policy support for sexual minorities and HIV-related outcomes among men who have sex with men in the United States, 2008-2014
Journal of Acquired Immune Deficiency Syndromes, 85 (1), 39-45. doi: 10.1097/QAI.0000000000002395. PMCID: PMC7429252.

Williams LD, Ibragimov U, Tempalski B, Stall R, Satcher Johnson A, Wang G, Cooper HLF, Friedman SR (2020).
Trends over time in HIV prevalence among people who inject drugs in 89 large US metropolitan statistical areas, 1992-2013
Annals of Epidemiology, 45, 12-23. doi: 10.1016/j.annepidem.2020.03.011. PMCID: PMC7430257.

Tempalski B, Beane S, Cooper HLF, Friedman SR, McKetta SC, Ibragimov U, Williams LD, Stall R (2020).
Structural determinants of Black MSM HIV testing coverage (2011-2016)
AIDS and Behavior, 24 (9), 2572-2587. doi: 10.1007/s10461-020-02814-4. PMCID: PMC7444860.

Linton SL, Cooper HLF, Chen YT, Khan MA, Wolfe ME, Ross Z, Des Jarlais DC, Friedman SR, Tempalski B, Broz D, Semaan S, Wejnert C, Paz-Bailey G (2020).
Mortgage discrimination and racial/ethnic concentration are associated with same-race/ethnicity partnering among people who inject drugs in 19 US cities
Journal of Urban Health, 97 (1), 88-104. doi: 10.1007/s11524-019-00405-w. PMCID: PMC7010885.

Tempalski B, Williams LD, West BS, Cooper HLF, Beane S, Ibragimov U, Friedman SR (2020).
Predictors of historical change in drug treatment coverage among people who inject drugs in 90 large metropolitan areas in the USA, 1993-2007
Substance Abuse Treatment, Prevention and Policy, 15 (1), 3. doi: 10.1186/s13011-019-0235-0. PMCID: PMC6953254.

Ibragimov U, Beane S, Friedman SR, Komro K, Adimora AA, Edwards JK, Williams LD, Tempalski B, Livingston MD, Stall RD, Wingood GM, Cooper HLF (2019).
States with higher minimum wages have lower STI rates among women: Results of an ecological study of 66 US metropolitan areas, 2003-2015
PLoS One, 14 (10), e0223579. doi: 10.1371/journal.pone.0223579. PMCID: PMC6785113.

Ibragimov U, Beane S, Friedman SR, Smith JC, Tempalski B, Williams L, Adimora AA, Wingood GM, McKetta S, Stall RD, Cooper HL (2020).
Police killings of Black people and rates of sexually transmitted infections: A cross-sectional analysis of 75 large US metropolitan areas, 2016
Sexually Transmitted Infections, 96 (6), 429-431. doi: 10.1136/sextrans-2019-054026. PMCID: PMC7377537.

Tempalski B, Cooper HLF, Kelley ME, Linton SL, Wolfe ME, Chen YT, Ross Z, Des Jarlais DC, Friedman SR, Williams LD, Semaan S, DiNenno E, Wejnert C, Broz D, Paz-Bailey G (2019).
Identifying which place characteristics are associated with the odds of recent HIV testing in a large sample of people who inject drugs in 19 US metropolitan areas
AIDS and Behavior, 23 (2), 318-335. doi: 10.1007/s10461-018-2217-z. PMCID: PMC6318077.

Ibragimov U, Beane S, Adimora AA, Friedman SR, Williams L, Tempalski B, Stall R, Wingood G, Hall HI, Johnson AS, Cooper HLF (2019).
Relationship of racial residential segregation to newly diagnosed cases of HIV among Black heterosexuals in US metropolitan areas, 2008-2015
Journal of Urban Health, 96 (6), 856-867. doi: 10.1007/s11524-018-0303-1. PMCID: PMC6904685.

Tempalski B, Cleland CM, Williams LD, Cooper HLF, Friedman SR (2018).
Change and variability in drug treatment coverage among people who inject drugs in 90 large metropolitan areas in the USA, 1993-2007
Substance Abuse Treatment, Prevention and Policy, 13, 28. doi: 10.1186/s13011-018-0165-2. PMCID: PMC6085615.

Friedman SR, Tempalski B, Brady JE, West BS, Pouget ER, Williams LD, Des Jarlais DC, Cooper HL (2016).
Income inequality, drug-related arrests, and the health of people who inject drugs: Reflections on seventeen years of research
International Journal of Drug Policy, 32, 11-16. doi: 10.1016/j.drugpo.2016.03.003. PMCID: PMC5344442.

Cooper HL, West B, Linton S, Hunter-Jones J, Zlotorzynska M, Stall R, Wolfe ME, Williams L, Hall HI, Cleland C, Tempalski B, Friedman SR (2016).
Contextual predictors of injection drug use among Black adolescents and adults in US metropolitan areas, 1993-2007
American Journal of Public Health, 106 (3), 517-526. doi: 10.2105/AJPH.2015.302911. PMCID: PMC4815709.

Friedman SR, Rossi D (2015).
Some musings about big events and the past and future of drug use and of HIV and other epidemics
Substance Use and Misuse, 50 (7), 899-902. doi: 10.3109/10826084.2015.1018752. PMCID: PMC4792193.