Addressing Health Disparities in HIV/AIDS Clinical Trials (ACT Project)
Funded by: National Institute of Allergy and Infectious Diseases
Project dates: November 2003 - October 2005
Principal Investigator: Mildvan D
Principal Investigator: Gwadz, Marya (Co-Investigator)
Co-Investigator: Leonard, Noelle

Although HIV/AIDS disproportionately affects African Americans and Latinos in the U.S., these groups are underrepresented in HIV/AIDS clinical trials. AIDS clinical trials (ACTs) are research studies in which new medications and treatment regimens for HIV/AIDS and their complications are tested for their safety and effectiveness in humans. The ACT1 study developed and evaluated the efficacy of a pilot behavioral small group intervention culturally targeted to African American and Latino persons living with HIV/AIDS, and also used mixed methods to explore barriers to ACTs that this population may experience.

Related Publications
Gwadz MV, Cylar K, Leonard NR, Riedel M, Herzog N, Arredondo GN, Cleland CM, Aguirre M, Marshak A, Mildvan D, Project ACT Collaborative Study Team (2010).
An exploratory behavioral intervention trial to improve rates of screening for AIDS clinical trials among racial/ethnic minority and female persons living with HIV/AIDS
AIDS and Behavior, 14 (3), 639-648. doi: 10.1007/s10461-009-9539-9.

Gwadz MV, Leonard NR, Nakagawa A, Cylar K, Finkelstein M, Herzog N, Tharaken M, Mildvan D (2006).
Gender differences in attitudes toward AIDS clinical trials among urban HIV-infected individuals from racial and ethnic minority backgrounds
AIDS Care, 18 (7), 786-794. doi: 10.1080/09540120500428952.

Gwadz MV, Leonard NR, Cleland CM, Riedel M, Banfield A, Mildvan D (2011).
The effect of peer-driven intervention on rates of screening for AIDS clinical trials among African Americans and Hispanics
American Journal of Public Health, 101 (6), 1096-1102. doi: 10.2105/AJPH.2010.196048. PMCID: PMC3093288.

Engel S, Gwadz MV, Cleland CM (2013).
The experience of screening for HIV/AIDS medical studies among African-American/Black and Latino/Hispanic persons living with HIV/AIDS: A mixed-methods exploration
Journal of AIDS Clinical Research, 4 (6), 1000223. doi: 10.4172/2155-6113.1000223. PMCID: PMC4443749.