ResearchProjects

Iron and Folic Acid Supplementation Strategies During Pregnancy and Adverse Pregnancy Outcomes In Botswana
Funded by: Eunice Kennedy Shriver National Institute of Child Health and Human Development
Project dates: August 2020 - July 2025
Principal Investigator: Caniglia, Ellen
PROJECT DESCRIPTION

Adverse pregnancy outcomes is extremely high in Sub-Saharan African countries including Botswana, especially among HIV-positive women. Daily iron and folic acid supplementation during pregnancy could reduce adverse pregnancy outcomes by reducing maternal anemia. However, the effectiveness of supplementation in subgroups defined by HIV status, anemia, gestational age, and other clinical, demographic and geographic factors remains unknown and compliance with supplementation guidelines is variable (<50% in Botswana).

Using the data and infrastructure from an ongoing birth outcomes surveillance study in Botswana, the study will:

  • Estimate the effect of iron and folic acid supplementation during pregnancy on adverse pregnancy outcomes by HIV status, anemia, gestational age, and other key subgroups to identify populations that would benefit most from intervention;
  • Develop and test the feasibility of an intervention to provide supplementation to pregnant women in Botswana.
Abstract on NIH RePORTER