Implementation Science to Optimize HIV Prevention in East Africa PEPFAR Programs
Funded by: National Institute of Allergy and Infectious Diseases
Project dates: May 2012 - April 2016
Principal Investigator: Braithwaite, R. Scott

The U.S. President’s Emergency plan for AIDS Relief (PEPFAR) aims to save millions of lives and achieve an AIDS-free generation. HIV positive individuals not retained in care are a critical problem and a barrier to achieving better health outcomes for the individuals and their communities. The project expanded a previous model of HIV in order to evaluate the benefits and value of retention-in-care interventions in East Africa, and identified the packages of retention interventions that will maximize health outcomes for patients based on patient, program, and health system characteristics. This study assessed the value of retention-in-care interventions and compared the value of these interventions to find the best ways to maximize resources and improve health outcomes.

Abstract on NIH RePORTER
Related Publications
Li L, Uyei J, Nucifora KA, Kessler J, Stevens ER, Bryant K, Braithwaite RS (2018).
Using value of information methods to determine the optimal sample size for effectiveness trials of alcohol interventions for HIV-infected patients in East Africa
BMC Health Services Research, 18 (1), 590. doi: 10.1186/s12913-018-3356-7. PMCID: PMC6069863.

Patel AR, Kessler J, Braithwaite RS, Nucifora KA, Thirumurthy H, Zhou Q, Lester RT, Marra CA (2017).
Economic evaluation of mobile phone text message interventions to improve adherence to HIV therapy in Kenya
Medicine, 96 (7), e6078. doi: 10.1097/MD.0000000000006078. PMCID: PMC5319505.

Kessler J, Nucifora K, Li L, Uhler L, Braithwaite S (2015).
Impact and cost-effectiveness of hypothetical strategies to enhance retention in care within HIV treatment programs in east Africa
Value in Health, 18 (8), 946-955. doi: 10.1016/j.jval.2015.09.2940. PMCID: PMC4696404.