Emergency Department Initiated Oral Naltrexone for Patients with Moderate to Severe Alcohol Use Disorder: A Pilot Feasibility Study
Funded by: Addiction Institute at Mount Sinai
Project dates: January 2021 - December 2021
Principal Investigator: Cowan, Ethan

This study recruited Emergency Department (ED) patients with moderate to severe alcohol use disorder (AUD) who were interested in initiating medication assisted treatment (MAT).  The study was split into two phases.  The first phase used implementation science strategies to strengthen existing non-targeted ED based AUD screening program and optimize feasibility, acceptability and linkage pathways.  The second phase incorporated lessons learned from the first phase to initiate ED patients on MAT for AUD in the form of oral naltrexone.  The primary outcome for both phase 1 and phase 2 was engagement in comprehensive addiction treatment at 14 and 30 days post enrollment.