ResearchPublications

This cross-sectional study included 18,797 participants from 6 longitudinal cohorts (CARDIA, FHS Gen III, HCHS/SOL, MESA, MiHeart, and REGARDS), and 5,806 of them had high-sensitivity C-reactive protein (hs-CRP) measurements. We found that exclusive electronic cigarette (EC) use was associated with significantly lower hs-CRP levels compared to exclusive combustible cigarette use, suggesting a potentially lower inflammatory burden. hs-CRP levels in dual users and former smokers currently using EC were comparable to those observed in exclusive cigarette smokers. Exclusive EC users showed no significant difference in hs-CRP levels compared to never cigarette smokers. These findings have important implications for tobacco regulation, public health, and clinical practice, highlighting the need for continued monitoring of potential EC-related health impacts.

Yao ZQ, Tasdighi E, Dardari ZA, Erhabor J, Jha KK, Osuji N, Rajan T, Boakye E, Rodriguez CJ, Lima JAC, Judd SE, Feldman T, Fialkow JA, Vasan RS, El-Shahawy O, Benjamin EJ, Bhatnagar A, Defilippis AP, Nasir K, Blaha MJ (2024).
Use of e-cigarettes, traditional combustible cigarettes, and high sensitivity C-reactive protein: The Cross Cohort Collaboration
American Heart Journal [Epub 2024 Oct 24]. doi: 10.1016/j.ahj.2024.10.012.