ResearchPublications

Sleep disturbance is associated with missing PrEP doses among young Black sexual minority men in the N2 study
Abstract

PrEP uptake and adherence among young Black sexual minority men (YBSMM), has been sub-optimal. Multiple studies identified sleep as an important determinant of medication adherence, although it has not been examined with regard to PrEP among YBSMM. This study utilized data collected from HIV-negative cisgender YBSMM in the Neighborhoods and Networks (N2) study in Chicago using PrEP (N = 70). Sleep quality was measured using the PHQ-9 and PrEP adherence questions were adapted from Reynolds et al., 2004. Bivariate and multivariable regression analyses were used to estimate associations between sleep and missing PrEP doses, controlling for relevant demographic and behavioral factors. YBSMM who reported sleep disturbance a moderate amount of time (aOR 7.59 [1.05 to 54.57]) were more likely to miss taking PrEP because they had too many pills to take. Sleep quality is an overlooked determinant of medication adherence, and may negatively impact YBSMM’s ability to consistently take PrEP.

Full citation:
Pagkas-Bather J, Duncan DT, Chen YT, Cursio J, Del Vecchio N, Mayer KH, Knox J, Hanson H, Eavou R, Schneider JA (2022).
Sleep disturbance is associated with missing PrEP doses among young Black sexual minority men in the N2 study
AIDS and Behavior [Epub 2022 Jun 4]. doi: 10.1007/s10461-022-03711-8.